A Tetravalent Dengue Vaccine Based on a Complex Adenovirus Vector Provides Significant Protection in Rhesus Monkeys against All Four Serotypes of Dengue Virus

Nearly a third of the human population is at risk of infection with the four serotypes of dengue viruses, and it is estimated that more than 100 million infections occur each year. A licensed vaccine for dengue viruses has become a global health priority. A major challenge to developing a dengue vac...

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Main Authors: Raviprakash, Kanakatte, Wang, Danher, Ewing, Dan, Holman, David H., Block, Karla, Woraratanadharm, Jan, Chen, Lan, Hayes, Curtis, Dong, John Y., Porter, Kevin
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2008
Assuntos:
Vaccines and Antiviral Agents
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2446963/
https://ncbi.nlm.nih.gov/pubmed/18480438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02724-07
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