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Functional Domains and the Antiviral Effect of the Double-Stranded RNA-Dependent Protein Kinase PKR from Paralichthys olivaceus

The double-stranded RNA (dsRNA)-dependent protein kinase PKR is thought to mediate a conserved antiviral pathway by inhibiting viral protein synthesis via the phosphorylation of the alpha subunit of eukaryotic initiation factor 2 (eIF2α). However, little is known about the data related to the lower...

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Библиографические подробности
Главные авторы: Zhu, Rong, Zhang, Yi-Bing, Zhang, Qi-Ya, Gui, Jian-Fang
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology (ASM) 2008
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2446945/
https://ncbi.nlm.nih.gov/pubmed/18448522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02385-07
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