Activation of a Frizzled-2/β-adrenergic receptor chimera promotes Wnt signaling and differentiation of mouse F9 teratocarcinoma cells via Gαo and Gαt

The frizzled gene family of putative Wnt receptors encodes proteins that have a seven-transmembrane-spanning motif characteristic of G protein-linked receptors, though no loss-of-function studies have demonstrated a requirement for G proteins for Frizzled signaling. We engineered a Frizzled-2 chimer...

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Bibliografiske detaljer
Main Authors: Liu, Xunxian, Liu, Tong, Slusarski, Diane C., Yang-Snyder, Julia, Malbon, Craig C., Moon, Randall T., Wang, Hsien-yu
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 1999
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC24445/
https://ncbi.nlm.nih.gov/pubmed/10588714
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