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WNT Stimulation Dissociates a Frizzled 4 Inactive-State Complex with Gα(12/13)
Frizzleds (FZDs) are unconventional G protein–coupled receptors that belong to the class Frizzled. They are bound and activated by the Wingless/Int-1 lipoglycoprotein (WNT) family of secreted lipoglycoproteins. To date, mechanisms of signal initiation and FZD–G protein coupling remain poorly underst...
में बचाया:
| में प्रकाशित: | Mol Pharmacol |
|---|---|
| मुख्य लेखकों: | , , , , , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
The American Society for Pharmacology and Experimental Therapeutics
2016
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5034691/ https://ncbi.nlm.nih.gov/pubmed/27458145 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.116.104919 |
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