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Wnt-5a/Frizzled9 Receptor Signaling through the Gα(o)-Gβγ Complex Regulates Dendritic Spine Formation

Wnt ligands play crucial roles in the development and regulation of synapse structure and function. Specifically, Wnt-5a acts as a secreted growth factor that regulates dendritic spine formation in rodent hippocampal neurons, resulting in postsynaptic development that promotes the clustering of the...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Ramírez, Valerie T., Ramos-Fernández, Eva, Henríquez, Juan Pablo, Lorenzo, Alfredo, Inestrosa, Nibaldo C.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5009279/
https://ncbi.nlm.nih.gov/pubmed/27402827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.722132
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