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Wnt-5a/Frizzled9 Receptor Signaling through the Gα(o)-Gβγ Complex Regulates Dendritic Spine Formation
Wnt ligands play crucial roles in the development and regulation of synapse structure and function. Specifically, Wnt-5a acts as a secreted growth factor that regulates dendritic spine formation in rodent hippocampal neurons, resulting in postsynaptic development that promotes the clustering of the...
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Publicado no: | J Biol Chem |
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Main Authors: | , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Biochemistry and Molecular Biology
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5009279/ https://ncbi.nlm.nih.gov/pubmed/27402827 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.722132 |
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