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Negative feedback regulation of Wnt signaling by Gβγ-mediated reduction of Dishevelled

Wnt signaling is known to be important for diverse embryonic and post-natal cellular events and be regulated by the proteins Dishevelled and Axin. Although Dishevelled is activated by Wnt and involved in signal transduction, it is not clear how Dishevelled-mediated signaling is turned off. We report...

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Detalhes bibliográficos
Main Authors: Jung, Hwajin, Kim, Hyun Joon, Lee, Suk Kyung, Kim, Rokki, Kopachik, Will, Han, Jin-Kwan, Jho, Eek-hoon
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Society of Medical Biochemistry and Molecular Biology 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2772972/
https://ncbi.nlm.nih.gov/pubmed/19561403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3858/emm.2009.41.10.076
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