Crystal structures of two human vitronectin, urokinase and urokinase receptor complexes

The urokinase receptor (uPAR) can recognize several ligands. The structural basis for this multiple ligand recognition by uPAR is unknown. This study reports the crystal structures of uPAR in complex with both urokinase (uPA) and vitronectin and reveal that uPA occupies the central cavity of the rec...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Huai, Qing, Zhou, Aiwu, Lin, Lin, Mazar, Andrew P, Parry, Graham C, Callahan, Jennifer, Shaw, David E, Furie, Bruce, Furie, Barbara C, Huang, Mingdong
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2008
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2443823/
https://ncbi.nlm.nih.gov/pubmed/18376415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1404
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk