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Crystal structures of two human vitronectin, urokinase and urokinase receptor complexes
The urokinase receptor (uPAR) can recognize several ligands. The structural basis for this multiple ligand recognition by uPAR is unknown. This study reports the crystal structures of uPAR in complex with both urokinase (uPA) and vitronectin and reveal that uPA occupies the central cavity of the rec...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2443823/ https://ncbi.nlm.nih.gov/pubmed/18376415 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1404 |
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