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The interplay between hMLH1 and hMRE11: role in MMR and the effect of hMLH1 mutations

Our previous studies indicate that hMRE11 plays a role in MMR, and this function of hMRE11 is most likely mediated by the hMLH1-hMRE11 interaction. Here, we explored the functional implications of the hMLH1-hMRE11 interaction in MMR and the effects of hMLH1 mutations on their interaction. Our in vit...

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Autors principals: Zhao, Nianxi, Zhu, Fengxue, Yuan, Fenghua, Haick, Anoria K., Fukushige, Shinichi, Gu, Liya, Her, Chengtao
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2443822/
https://ncbi.nlm.nih.gov/pubmed/18373977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2008.03.082
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