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hMRE11 deficiency leads to microsatellite instability and defective DNA mismatch repair
DNA mismatch repair (MMR) is essential in the surveillance of accurate transmission of genetic information, and defects in this pathway lead to microsatellite instability and hereditary nonpolyposis colorectal cancer (HNPCC). Our previous study raised the possibility that hMRE11 might be involved in...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1299302/ https://ncbi.nlm.nih.gov/pubmed/15864295 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400392 |
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