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Human AP endonuclease suppresses DNA mismatch repair activity leading to microsatellite instability

The multifunctional mammalian apurinic/apyrimidinic (AP) endonuclease (APE) participates in the repair of AP sites in the cellular DNA as well as participating in the redox regulation of the transcription factor function. The function of APE is considered as the rate-limiting step in DNA base excisi...

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Detalhes bibliográficos
Main Authors: Chang, In-Youb, Kim, Soo-Hyun, Cho, Hyun-Ju, Lee, Do Young, Kim, Mi-Hwa, Chung, Myung-Hee, You, Ho Jin
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1201336/
https://ncbi.nlm.nih.gov/pubmed/16147991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki829
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