The Thymine DNA Glycosylase MBD4 Represses Transcription and Is Associated with Methylated p16(INK4a) and hMLH1 Genes

Epigenetic silencing through methyl-CpG (mCpG) is implicated in many biological patterns such as genome imprinting, X chromosome inactivation, and cancer development. In this process, the mCpG binding domain (MBD) proteins play an essential role in transmitting epigenetic information to downstream r...

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Detalhes bibliográficos
Main Authors: Kondo, Emiko, Gu, Zhaodi, Horii, Akira, Fukushige, Shinichi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1140624/
https://ncbi.nlm.nih.gov/pubmed/15899845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.11.4388-4396.2005
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