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The Thymine DNA Glycosylase MBD4 Represses Transcription and Is Associated with Methylated p16(INK4a) and hMLH1 Genes
Epigenetic silencing through methyl-CpG (mCpG) is implicated in many biological patterns such as genome imprinting, X chromosome inactivation, and cancer development. In this process, the mCpG binding domain (MBD) proteins play an essential role in transmitting epigenetic information to downstream r...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Microbiology
2005
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1140624/ https://ncbi.nlm.nih.gov/pubmed/15899845 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.11.4388-4396.2005 |
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