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GPR17: Molecular modeling and dynamics studies of the 3-D structure and purinergic ligand binding features in comparison with P2Y receptors

BACKGROUND: GPR17 is a G-protein-coupled receptor located at intermediate phylogenetic position between two distinct receptor families: the P2Y and CysLT receptors for extracellular nucleotides and cysteinyl-LTs, respectively. We previously showed that GPR17 can indeed respond to both classes of end...

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Autori principali: Parravicini, Chiara, Ranghino, Graziella, Abbracchio, Maria P, Fantucci, Piercarlo
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2443813/
https://ncbi.nlm.nih.gov/pubmed/18533035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-9-263
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