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Myosin Regulatory Light Chain Phosphorylation Attenuates Cardiac Hypertrophy
Hyperphosphorylation of myosin regulatory light chain (RLC) in cardiac muscle is proposed to cause compensatory hypertrophy. We therefore investigated potential mechanisms in genetically modified mice. Transgenic (TG) mice were generated to overexpress Ca(2+)/calmodulin-dependent myosin light chain...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Biochemistry and Molecular Biology
2008
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2443673/ https://ncbi.nlm.nih.gov/pubmed/18474588 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M802605200 |
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