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Murine Leukemia Virus Spreading in Mice Impaired in the Biogenesis of Secretory Lysosomes and Ca(2+)-Regulated Exocytosis

BACKGROUND: Retroviruses have been observed to bud intracellularly into multivesicular bodies (MVB), in addition to the plasma membrane. Release from MVB is thought to occur by Ca(2+)-regulated fusion with the plasma membrane. PRINCIPAL FINDINGS: To address the role of the MVB pathway in replication...

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Bibliografiske detaljer
Main Authors: Chan, Wai-Tsing, Sherer, Nathan M., Uchil, Pradeep D., Novak, Edward K., Swank, Richard T., Mothes, Walther
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2443282/
https://ncbi.nlm.nih.gov/pubmed/18629000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002713
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