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Glucose regulates the effects of leptin on hypothalamic POMC neurons
Leptin is believed to exert its potent appetite-suppressing effects via stimulation of hypothalamic anorexigenic proopiomelanocortin (POMC)-containing neurons and inhibition of orexigenic agouti-related protein (AgRP) neurons. We show here that at 11 mM glucose leptin excites POMC cells. At 5 mM glu...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2443183/ https://ncbi.nlm.nih.gov/pubmed/18599453 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0800952105 |
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