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Glucose regulates the effects of leptin on hypothalamic POMC neurons

Leptin is believed to exert its potent appetite-suppressing effects via stimulation of hypothalamic anorexigenic proopiomelanocortin (POMC)-containing neurons and inhibition of orexigenic agouti-related protein (AgRP) neurons. We show here that at 11 mM glucose leptin excites POMC cells. At 5 mM glu...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Ma, Xiaosong, Zubcevic, Lejla, Ashcroft, Frances M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2008
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2443183/
https://ncbi.nlm.nih.gov/pubmed/18599453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0800952105
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