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Positional stability of single double-strand breaks in mammalian cells
Formation of cancerous translocations requires the illegitimate joining of chromosomes containing double-strand breaks (DSBs). It is unknown how broken chromosome ends find their translocation partners within the cell nucleus. Here, we have visualized and quantitatively analysed the dynamics of sing...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2007
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2442898/ https://ncbi.nlm.nih.gov/pubmed/17486118 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb1591 |
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