The PPAR-γ Agonist 15-Deoxy-Δ (12,14)-Prostaglandin J(2) Attenuates Microglial Production of IL-12 Family Cytokines: Potential Relevance to Alzheimer's Disease

Accumulation of amyloid-β peptide (Aβ) appears to contribute to the pathogenesis of Alzheimer's disease (AD). Therapeutic hope for the prevention or removal of Aβ deposits has been placed in strategies involving immunization against the Aβ peptide. Initial Aβ immunization studies in animal mode...

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Autori principali: Xu, Jihong, Barger, Steven W., Drew, Paul D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi Publishing Corporation 2008
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2442897/
https://ncbi.nlm.nih.gov/pubmed/18615183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2008/349185
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