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p38 MAP kinase mediates arsenite-induced apoptosis through FOXO3a activation and induction of Bim transcription
Sodium arsenite induces apoptosis in PC12 cells by activating the stress-activated p38 MAP kinase and the pro-apoptotic Bcl-2 family protein Bim(EL). However, the relationship between p38 and Bim(EL) in this apoptosis has not been fully defined. Here, we report that sodium arsenite stimulates the pr...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2442769/ https://ncbi.nlm.nih.gov/pubmed/18465250 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10495-008-0218-5 |
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