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Lead decreases cell survival, proliferation, and neuronal differentiation of primary cultured adult neural precursor cells through activation of the JNK and p38 MAP kinases

Adult hippocampal neurogenesis is the process whereby adult neural precursor cells (aNPCs) in the subgranular zone (SGZ) of the dentate gyrus (DG) generate adult-born, functional neurons in the hippocampus. This process is modulated by various extracellular and intracellular stimuli, and the adult-b...

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Опубликовано в: :Toxicol In Vitro
Главные авторы: Engstrom, Anna, Wang, Hao, Xia, Zhengui
Формат: Artigo
Язык:Inglês
Опубликовано: 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4457670/
https://ncbi.nlm.nih.gov/pubmed/25967738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tiv.2015.05.001
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