Prostaglandin E Receptor Type 4-associated Protein Interacts Directly with NF-κB1 and Attenuates Macrophage Activation

Macrophage activation participates pivotally in the pathophysiology of chronic inflammatory diseases, including atherosclerosis. Through the receptor EP4, prostaglandin E(2) (PGE(2)) exerts an anti-inflammatory action in macrophages, suppressing stimulus-induced expression of certain proinflammatory...

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Detalhes bibliográficos
Main Authors: Minami, Manabu, Shimizu, Koichi, Okamoto, Yoshihisa, Folco, Eduardo, Ilasaca, Marco-Lopez, Feinberg, Mark W., Aikawa, Masanori, Libby, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Mechanisms of Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2442287/
https://ncbi.nlm.nih.gov/pubmed/18270204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M709663200
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