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GRK5 deficiency exaggerates inflammatory changes in TgAPPsw mice
BACKGROUND: Deficiency of membrane G-protein coupled receptor (GPCR) kinase-5 (GRK5) recently has been linked to early AD pathogenesis, and has been suggested to contribute to augmented microglial activation in vitro by sensitizing relevant GPCRs. However, GRK5 deficient mice did not show any signs...
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| Asıl Yazarlar: | , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
BioMed Central
2008
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2442054/ https://ncbi.nlm.nih.gov/pubmed/18522748 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-5-24 |
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