GRK5 Deficiency Leads to Selective Basal Forebrain Cholinergic Neuronal Vulnerability

Why certain diseases primarily affect one specific neuronal subtype rather than another is a puzzle whose solution underlies the development of specific therapies. Selective basal forebrain cholinergic (BFC) neurodegeneration participates in cognitive impairment in Alzheimer’s disease (AD), yet the...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: He, Minchao, Singh, Prabhakar, Cheng, Shaowu, Zhang, Qiang, Peng, Wei, Ding, XueFeng, Li, Longxuan, Liu, Jun, Premont, Richard T., Morgan, Dave, Burns, Jeffery M., Swerdlow, Russell H., Suo, William Z.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4872166/
https://ncbi.nlm.nih.gov/pubmed/27193825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep26116
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