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Exploring the impact of polyproline II (P(II)) conformational bias on the binding of peptides to the SEM-5 SH3 domain

The left-handed polyproline II helical structure (P(II)) is observed to be a dominant conformation in the disordered states of protein and small polypeptide chains, even when no prolines are present in the sequence. Recently, in work by Ferreon and Hilser, the energetics associated with Ala and Gly...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Whitten, Steven T., Yang, Huan-Wang, Fox, Robert O., Hilser, Vincent J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Cold Spring Harbor Laboratory Press 2008
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2441998/
https://ncbi.nlm.nih.gov/pubmed/18577755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.033647.107
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