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Exploring the impact of polyproline II (P(II)) conformational bias on the binding of peptides to the SEM-5 SH3 domain

The left-handed polyproline II helical structure (P(II)) is observed to be a dominant conformation in the disordered states of protein and small polypeptide chains, even when no prolines are present in the sequence. Recently, in work by Ferreon and Hilser, the energetics associated with Ala and Gly...

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Detaylı Bibliyografya
Asıl Yazarlar: Whitten, Steven T., Yang, Huan-Wang, Fox, Robert O., Hilser, Vincent J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Cold Spring Harbor Laboratory Press 2008
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2441998/
https://ncbi.nlm.nih.gov/pubmed/18577755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.033647.107
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