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Genomic Instability Is Associated with Natural Life Span Variation in Saccharomyces cerevisiae

Increasing genomic instability is associated with aging in eukaryotes, but the connection between genomic instability and natural variation in life span is unknown. We have quantified chronological life span and loss-of-heterozygosity (LOH) in 11 natural isolates of Saccharomyces cerevisiae. We show...

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Detalhes bibliográficos
Main Authors: Qin, Hong, Lu, Meng, Goldfarb, David S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2441830/
https://ncbi.nlm.nih.gov/pubmed/18628831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002670
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