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Peroxiredoxins play a major role in protecting Trypanosoma cruzi against macrophage- and endogenously-derived peroxynitrite

There is increasing evidence that Trypanosoma cruzi antioxidant enzymes play a key immune evasion role by protecting the parasite against macrophage-derived reactive oxygen and nitrogen species. Using T. cruzi transformed to overexpress the peroxiredoxins TcCPX (T. cruzi cytosolic tryparedoxin perox...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Piacenza, Lucía, Peluffo, Gonzalo, Alvarez, María Noel, Kelly, John M., Wilkinson, Shane R., Radi, Rafael
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2441817/
https://ncbi.nlm.nih.gov/pubmed/17973627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20071138
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