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Aurora A Phosphorylates MCAK to Control Ran-dependent Spindle Bipolarity
During mitosis, mitotic centromere-associated kinesin (MCAK) localizes to chromatin/kinetochores, a cytoplasmic pool, and spindle poles. Its localization and activity in the chromatin region are regulated by Aurora B kinase; however, how the cytoplasmic- and pole-localized MCAK are regulated is curr...
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Main Authors: | , , |
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Format: | Artigo |
Language: | Inglês |
Published: |
The American Society for Cell Biology
2008
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2441684/ https://ncbi.nlm.nih.gov/pubmed/18434591 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-02-0198 |
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