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A Novel Role for Cdk1/Cyclin B in Regulating B-Raf Activation at Mitosis

MAPK activity is important during mitosis for spindle assembly and maintenance of the spindle checkpoint arrest. We previously identified B-Raf as a critical activator of the MAPK cascade during mitosis in Xenopus egg extracts and showed that B-Raf activation is regulated in an M-phase–dependent man...

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Hlavní autoři: Borysov, Sergiy I., Guadagno, Thomas M.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Cell Biology 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2441668/
https://ncbi.nlm.nih.gov/pubmed/18434602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E07-07-0679
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