Insulin Stimulates Phosphatidylinositol 3-Phosphate Production via the Activation of Rab5

Phosphatidylinositol 3-phosphate (PI(3)P) plays an important role in insulin-stimulated glucose uptake. Insulin promotes the production of PI(3)P at the plasma membrane by a process dependent on TC10 activation. Here, we report that insulin-stimulated PI(3)P production requires the activation of Rab...

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Autori principali: Lodhi, Irfan J., Bridges, Dave, Chiang, Shian-Huey, Zhang, Yanling, Cheng, Alan, Geletka, Lynn M., Weisman, Lois S., Saltiel, Alan R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Cell Biology 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2441665/
https://ncbi.nlm.nih.gov/pubmed/18434594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-01-0105
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