A Variant of the Cockayne Syndrome B Gene ERCC6 Confers Risk of Lung Cancer

Cockayne syndrome B protein (ERCC6) plays an essential role in DNA repair. However, the Cockayne syndrome caused by the ERCC6 defect has not been linked to cancer predisposition; likely due to the fact that cells with severe disruption of the ERCC6 function are sensitive to lesion-induced apoptosis,...

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Main Authors: Lin, Zhongning, Zhang, Xuemei, Tuo, Jingsheng, Guo, Yongli, Green, Bridgett, Chan, Chi-Chao, Tan, Wen, Huang, Ying, Ling, Wenhua, Kadlubar, Fred F., Lin, Dongxin, Ning, Baitang
Format: Artigo
Jezik:Inglês
Izdano: 2008
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2441604/
https://ncbi.nlm.nih.gov/pubmed/17854076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/humu.20610
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