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Functional Single Nucleotide Polymorphism in IL-17A 3′ Untranslated Region is Targeted by miR-4480 in vitro and may be Associated with Age-Related Macular Degeneration
Age-related macular degeneration (AMD) is a leading cause of irreversible central vision loss in the elderly. Genetic factors contributing to AMD include single nucleotide polymorphisms (SNPs) in immune-related genes including CFH, C2, CFI, C9, and C3, thus implicating these pathways in AMD pathogen...
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Publicat a: | Environ Mol Mutagen |
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Autors principals: | , , , , , , |
Format: | Artigo |
Idioma: | Inglês |
Publicat: |
2015
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Matèries: | |
Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4714768/ https://ncbi.nlm.nih.gov/pubmed/26765636 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/em.21982 |
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