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Functional Single Nucleotide Polymorphism in IL-17A 3′ Untranslated Region is Targeted by miR-4480 in vitro and may be Associated with Age-Related Macular Degeneration

Age-related macular degeneration (AMD) is a leading cause of irreversible central vision loss in the elderly. Genetic factors contributing to AMD include single nucleotide polymorphisms (SNPs) in immune-related genes including CFH, C2, CFI, C9, and C3, thus implicating these pathways in AMD pathogen...

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Dades bibliogràfiques
Publicat a:Environ Mol Mutagen
Autors principals: Popp, Nicholas A., Yu, Dianke, Green, Bridgett, Chew, Emily Y., Ning, Baitang, Chan, Chi-Chao, Tuo, Jingsheng
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4714768/
https://ncbi.nlm.nih.gov/pubmed/26765636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/em.21982
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