Synergic effect of polymorphisms in ERCC6 5′ flanking region and complement factor H on age-related macular degeneration predisposition

This study investigates age-related macular degeneration (AMD) genetic risk factors through identification of a functional single-nucleotide polymorphism (SNP) and its disease association. We chose ERCC6 because of its roles in the aging process, DNA repair, and ocular degeneration from the gene dis...

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Bibliografiske detaljer
Main Authors: Tuo, Jingsheng, Ning, Baitang, Bojanowski, Christine M., Lin, Zhong-Ning, Ross, Robert J., Reed, George F., Shen, Defen, Jiao, Xiaodong, Zhou, Min, Chew, Emily Y., Kadlubar, Fred F., Chan, Chi-Chao
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2006
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1474016/
https://ncbi.nlm.nih.gov/pubmed/16754848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0603485103
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