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The Ubiquitin-like Protein Plic-1 Enhances the Membrane Insertion of GABA(A) Receptors by Increasing Their Stability within the Endoplasmic Reticulum

γ-Aminobutyric acid receptors (GABA(A)R) are the major sites of fast inhibitory neurotransmission in the brain, and a critical determinant for the efficacy of neuronal inhibition is the number of these receptors that are expressed on the neuronal cell surface. GABA(A)Rs are heteropentamers that can...

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Detalhes bibliográficos
Main Authors: Saliba, Richard S., Pangalos, Menelas, Moss, Stephen J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2441556/
https://ncbi.nlm.nih.gov/pubmed/18467327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M802077200
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