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Chemical carcinogens in non-enzymatic cytosine deamination: 3-isocyanatoacrylonitrile
Uracil has long been known as the main product of nitrosative cytosine deamination in aqueous solution. Recent mechanistic studies of cytosinediazonium ion suggest that the cation formed by its dediazoniation can ring-open to N-protonated (Z,s-cis)-3-isocyanatoacrylonitrile 7. Stereochemical prefere...
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| Main Authors: | , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Springer-Verlag
2006
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2441498/ https://ncbi.nlm.nih.gov/pubmed/16411080 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00894-005-0048-0 |
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