A near null variant of 12/15-LOX encoded by a novel SNP in ALOX15 and the risk of coronary artery disease: Assimes T560M in ALOX15 and the risk of CAD

OBJECTIVE: Murine genetic models suggest that function of the 12/15 LOX enzyme promotes atherosclerosis. We tested the hypothesis that exonic and/or promoter single nucleotide polymorphisms (SNPs) in the human 12/15-LOX gene (ALOX15) alter the risk of symptomatic coronary artery disease (CAD). METHO...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Assimes, Themistocles L., Knowles, Joshua W., Priest, James R., Basu, Analabha, Borchert, Astrid, Volcik, Kelly A., Grove, Megan L., Tabor, Holly K., Southwick, Audrey, Tabibiazar, Raymond, Sidney, Steve, Boerwinkle, Eric, Go, Alan S., Iribarren, Carlos, Hlatky, Mark A., Fortmann, Stephen P., Myers, Richard M., Kuhn, Hartmut, Risch, Neil, Quertermous, Thomas
Format: Artigo
Sprog:Inglês
Udgivet: 2007
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2440699/
https://ncbi.nlm.nih.gov/pubmed/17959182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.atherosclerosis.2007.09.003
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker