A near null variant of 12/15-LOX encoded by a novel SNP in ALOX15 and the risk of coronary artery disease: Assimes T560M in ALOX15 and the risk of CAD

OBJECTIVE: Murine genetic models suggest that function of the 12/15 LOX enzyme promotes atherosclerosis. We tested the hypothesis that exonic and/or promoter single nucleotide polymorphisms (SNPs) in the human 12/15-LOX gene (ALOX15) alter the risk of symptomatic coronary artery disease (CAD). METHO...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Assimes, Themistocles L., Knowles, Joshua W., Priest, James R., Basu, Analabha, Borchert, Astrid, Volcik, Kelly A., Grove, Megan L., Tabor, Holly K., Southwick, Audrey, Tabibiazar, Raymond, Sidney, Steve, Boerwinkle, Eric, Go, Alan S., Iribarren, Carlos, Hlatky, Mark A., Fortmann, Stephen P., Myers, Richard M., Kuhn, Hartmut, Risch, Neil, Quertermous, Thomas
Format: Artigo
Idioma:Inglês
Publicat: 2007
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2440699/
https://ncbi.nlm.nih.gov/pubmed/17959182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.atherosclerosis.2007.09.003
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars