Failure to replicate an association of SNPs in the oxidized LDL receptor gene (OLR1) with CAD

BACKGROUND: The lectin-like oxidized LDL receptor LOX-1 (encoded by OLR1) is believed to play a key role in atherogenesis and some reports suggest an association of OLR1 polymorphisms with myocardial infarction (MI). We tested whether single nucleotide polymorphisms (SNPs) in OLR1 are associated wit...

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Bibliografiske detaljer
Main Authors: Knowles, Joshua W, Assimes, Themistocles L, Boerwinkle, Eric, Fortmann, Stephen P, Go, Alan, Grove, Megan L, Hlatky, Mark, Iribarren, Carlos, Li, Jun, Myers, Richard, Risch, Neil, Sidney, Stephen, Southwick, Audrey, Volcik, Kelly A, Quertermous, Thomas
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2008
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2322963/
https://ncbi.nlm.nih.gov/pubmed/18384690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-9-23
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