Failure to replicate an association of SNPs in the oxidized LDL receptor gene (OLR1) with CAD

BACKGROUND: The lectin-like oxidized LDL receptor LOX-1 (encoded by OLR1) is believed to play a key role in atherogenesis and some reports suggest an association of OLR1 polymorphisms with myocardial infarction (MI). We tested whether single nucleotide polymorphisms (SNPs) in OLR1 are associated wit...

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Hlavní autoři: Knowles, Joshua W, Assimes, Themistocles L, Boerwinkle, Eric, Fortmann, Stephen P, Go, Alan, Grove, Megan L, Hlatky, Mark, Iribarren, Carlos, Li, Jun, Myers, Richard, Risch, Neil, Sidney, Stephen, Southwick, Audrey, Volcik, Kelly A, Quertermous, Thomas
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2008
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2322963/
https://ncbi.nlm.nih.gov/pubmed/18384690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-9-23
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