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Chromosomal Protein HMGN1 Modulates the Phosphorylation of Serine 1 in Histone H2A
Here we demonstrate that HMGN1, a nuclear protein that binds specifically to nucleosomes, modulates the level of histone H2A phosphorylation. In Hmgn1(-/-) cells, loss of HMGN1 elevates the steady-state levels of H2AS1ph throughout the cell cycle. In vitro, HMGN1 reduces the rate of Rsk2- and Msk1-m...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2440507/ https://ncbi.nlm.nih.gov/pubmed/17154547 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi0613271 |
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