Chromosomal protein HMGN1 enhances the rate of DNA repair in chromatin
We report that HMGN1, a nucleosome binding protein that destabilizes the higher-order chromatin structure, modulates the repair rate of ultraviolet light (UV)-induced DNA lesions in chromatin. Hmgn1(–/–) mouse embryonic fibroblasts (MEFs) are hypersensitive to UV, and the removal rate of photoproduc...
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| Publicado no: | EMBO J |
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| Principais autores: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC152887/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12660172/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg142 |
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