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Chromosomal protein HMGN1 enhances the rate of DNA repair in chromatin
We report that HMGN1, a nucleosome binding protein that destabilizes the higher-order chromatin structure, modulates the repair rate of ultraviolet light (UV)-induced DNA lesions in chromatin. Hmgn1(–/–) mouse embryonic fibroblasts (MEFs) are hypersensitive to UV, and the removal rate of photoproduc...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC152887/ https://ncbi.nlm.nih.gov/pubmed/12660172 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg142 |
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