Chromosomal protein HMGN1 enhances the rate of DNA repair in chromatin

We report that HMGN1, a nucleosome binding protein that destabilizes the higher-order chromatin structure, modulates the repair rate of ultraviolet light (UV)-induced DNA lesions in chromatin. Hmgn1(–/–) mouse embryonic fibroblasts (MEFs) are hypersensitive to UV, and the removal rate of photoproduc...

Popoln opis

Bibliografske podrobnosti

izdano v:	EMBO J
Principais autores:	Birger, Yehudit, West, Katherine L., Postnikov, Yuri V., Lim, Jae-Hwan, Furusawa, Takashi, Wagner, James P., Laufer, Craig S., Kraemer, Kenneth H., Bustin, Michael
Format:	Artigo
Jezik:	Inglês
Izdano:	Nature Publishing Group 2003
Teme:	Articles
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC152887/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12660172/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg142
Oznake:	Označite Brez oznak, prvi označite!