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Lipoic acid significantly restores, in rats, the age-related decline in vasomotion
Background and purpose: The age-related decline in vasorelaxation is largely due to ceramide-induced induction of phosphatase 2A (PP2A), which limits nitric oxide synthase (eNOS) phosphorylation at stimulatory sites. We hypothesized that ceramide accumulation was from an age-related loss of endothel...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2438266/ https://ncbi.nlm.nih.gov/pubmed/18297110 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.28 |
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