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Antimalarial drugs inhibit human 5-HT(3) and GABA(A) but not GABA(C) receptors

Background and purpose: Antimalarial compounds have been previously shown to inhibit rodent nicotinic acetylcholine (nACh) and 5-HT(3) receptors. Here, we extend these studies to include human 5-HT(3A), 5-HT(3AB), GABA(A) α1β2, GABA(A) α1β2γ2 and GABA(C) ρ1 receptors. Experimental approach: We exami...

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Detalhes bibliográficos
Main Authors: Thompson, A J, Lummis, S C R
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2438262/
https://ncbi.nlm.nih.gov/pubmed/18311193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.34
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