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Alternative translation of osteopontin generates intracellular and secreted isoforms that mediate distinct biological activities in dendritic cells

Osteopontin (Opn) contributes to diverse biological processes that include immune responses, vascularization, and bone formation. Until recently, studies describing the activities of Opn have focused on the cytokine-like properties of the secreted protein. Here, we show that alternative translation...

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Библиографические подробности
Главные авторы: Shinohara, Mari L., Kim, Hye-Jung, Kim, June-Ho, Garcia, Virgilio A., Cantor, Harvey
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2008
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2438233/
https://ncbi.nlm.nih.gov/pubmed/18480255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0802301105
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