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Alternative translation of osteopontin generates intracellular and secreted isoforms that mediate distinct biological activities in dendritic cells

Osteopontin (Opn) contributes to diverse biological processes that include immune responses, vascularization, and bone formation. Until recently, studies describing the activities of Opn have focused on the cytokine-like properties of the secreted protein. Here, we show that alternative translation...

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Detalhes bibliográficos
Main Authors: Shinohara, Mari L., Kim, Hye-Jung, Kim, June-Ho, Garcia, Virgilio A., Cantor, Harvey
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2438233/
https://ncbi.nlm.nih.gov/pubmed/18480255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0802301105
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