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Engagement of the Type-I interferon receptor on dendritic cells inhibits T helper 17 cell development: Central role of intracellular Osteopontin
Mechanisms that prevent inappropriate or excessive interleukin-17-producing T helper (Th17) cell responses after microbial infection may be necessary to avoid autoimmunity. Here, we define a pathway initiated by engagement of Type-I IFN receptor (IFNAR) expressed by dendritic cells (DC) that culmina...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2625293/ https://ncbi.nlm.nih.gov/pubmed/18619869 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2008.05.008 |
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