Llwytho...

Chaperone-dependent amyloid assembly protects cells from prion toxicity

Protein conformational diseases are associated with the aberrant accumulation of amyloid protein aggregates, but whether amyloid formation is cytotoxic or protective is unclear. To address this issue, we investigated a normally benign amyloid formed by the yeast prion [RNQ(+)]. Surprisingly, modest...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Douglas, Peter M., Treusch, Sebastian, Ren, Hong-Yu, Halfmann, Randal, Duennwald, Martin L., Lindquist, Susan, Cyr, Douglas M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2008
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2438228/
https://ncbi.nlm.nih.gov/pubmed/18480252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0802593105
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!