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Chaperone-dependent amyloid assembly protects cells from prion toxicity
Protein conformational diseases are associated with the aberrant accumulation of amyloid protein aggregates, but whether amyloid formation is cytotoxic or protective is unclear. To address this issue, we investigated a normally benign amyloid formed by the yeast prion [RNQ(+)]. Surprisingly, modest...
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| Huvudupphovsmän: | , , , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
National Academy of Sciences
2008
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2438228/ https://ncbi.nlm.nih.gov/pubmed/18480252 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0802593105 |
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