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Chaperone-dependent amyloid assembly protects cells from prion toxicity
Protein conformational diseases are associated with the aberrant accumulation of amyloid protein aggregates, but whether amyloid formation is cytotoxic or protective is unclear. To address this issue, we investigated a normally benign amyloid formed by the yeast prion [RNQ(+)]. Surprisingly, modest...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2438228/ https://ncbi.nlm.nih.gov/pubmed/18480252 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0802593105 |
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