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Screening for Amyloid Aggregation by Semi-Denaturing Detergent-Agarose Gel Electrophoresis

Amyloid aggregation is associated with numerous protein misfolding pathologies and underlies the infectious properties of prions, which are conformationally self-templating proteins that are thought to have beneficial roles in lower organisms. Amyloids have been notoriously difficult to study due to...

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Bibliografiske detaljer
Main Authors: Halfmann, Randal, Lindquist, Susan
Format: Artigo
Sprog:Inglês
Udgivet: MyJove Corporation 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2723713/
https://ncbi.nlm.nih.gov/pubmed/19066511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/838
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