Llwytho...

Agonist binding, agonist affinity and agonist efficacy at G protein-coupled receptors

Measurements of affinity and efficacy are fundamental for work on agonists both in drug discovery and in basic studies on receptors. In this review I wish to consider methods for measuring affinity and efficacy at G protein coupled receptors (GPCRs). Agonist affinity may be estimated in terms of the...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awdur: Strange, P G
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2008
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2437915/
https://ncbi.nlm.nih.gov/pubmed/18223670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707672
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